半岛bd体育手机客户端 介绍
基因名：
KIR2DL2 半岛bd体育手机客户端 别名： CD158B1； CD158b； NKAT-6； NKAT6； p58.2； KIR2DL2； killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 2； killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 2； killer cell immunoglobulin-like receptor 2DL2； CD158 antigen-like family member B1； MHC class I NK cell receptor； killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2； natural killer-associated transcript 6； p58 NK receptor CL-43； p58 natural killer cell receptor clone CL-43； NK细胞抑制性受体2DL2； 杀伤细胞免疫球蛋白样受体2DL2(KIR2DL2)； 背景信息：
KIR2DL2 (2DL2, formerly NKAT6, designated CD158b) is a 348 amino acid (aa) type I transmembrane glycoprotein that belongs to the human killer cell Ig?like receptor (KIR) family. KIRs are expressed on human CD56dim NK cells and T cell subsets, and regulate effector functions in the innate immune system.KIR2DL2 is receptor on natural killer (NK) cells for HLA-Cw1, 3, 7, and 8 allotypes. Inhibits the activity of NK cells thus preventing cell lysis.
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