半岛bd体育手机客户端 介绍
基因名：
KCNQ3 半岛bd体育手机客户端 别名： BFNC2； EBN2； KV7.3； KCNQ3； potassium voltage-gated channel subfamily Q member 3； potassium voltage-gated channel subfamily Q member 3； potassium voltage-gated channel subfamily KQT member 3； potassium channel subunit alpha KvLQT3； potassium channel, voltage gated KQT-like subfamily Q, member 3； potassium channel, voltage-gated, subfamily Q, member 3； potassium voltage-gated channel, KQT-like subfamily, member 3； voltage-gated potassium channel subunit Kv7.3； 电压门控钾通道亚基Kv7.3； 背景信息：
The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and one of two related proteins encoded by the KCNQ2 and KCNQ5 genes, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 2 (BFNC2), also known as epilepsy, benign neonatal type 2 (EBN2). Two variants encoding distinct isoforms have been found. [provided by RefSeq, Mar 2011]
标签：His-tag |
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