半岛bd体育手机客户端 介绍
基因名：
DHX15 半岛bd体育手机客户端 别名： DBP1； DDX15； PRP43； PRPF43； PrPp43p； hPrp43； DHX15； DEAH-box helicase 15； DEAH-box helicase 15； ATP-dependent RNA helicase DHX15； ATP-dependent RNA helicase #46； DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 15； DEAD/H box-15； DEAH (Asp-Glu-Ala-His) box helicase 15； DEAH (Asp-Glu-Ala-His) box polypeptide 15； DEAH box protein 15； RNA helicase 2； pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15； putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15； splicing factor Prp43； DHX15蛋白； 背景信息：
DEAD-box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure and ribosome/spliceosome assembly. Based on their distribution patterns, some members of this family may be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX15 (DEAH-box protein 15), also known as DHX15, DBP1 or HRH2, is a nuclear ATP-dependent RNA helicase that is involved in pre-mRNA splicing and is a member of the DEAH-box subfamily of DEAD-box proteins. Expressed throughout the body, DDX15 is a pre-mRNA processing factor that plays a role in spliceosome disassembly after the release of mature mRNA. When localized to the nucleoli, DDX15 is thought to interact with the La/SSB autoantigen, an RNA chaperone that functions in various intracellular processes. DDX15 is 795 amino acids in length and is the human ortholog of the S. cerevisiae protein Prp43. helicase 2.
标签：His-tag |
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