您的位置：首页 > 半岛bd体育手机客户端 中心 > Anti-Laminin subunit alpha-4 Antibody, clone 3H2
Anti-Laminin subunit alpha-4 Antibody, clone 3H2
| 半岛bd体育手机客户端 编号： | 4154551 |
| 规格： | clone 3H2, from mouse |
| 包装规格： | 100 μL |
| 半岛bd体育手机客户端 类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
半岛bd体育手机客户端 别名
Anti-Laminin subunit alpha-4 Antibody, clone 3H2
laminin, alpha 4, laminin subunit alpha-4, Laminin-8 subunit alpha, Laminin-9 subunit alpha, laminin alpha 4 chain, Laminin-14 subunit alpha
基本信息
| eCl@ss |
32160702
|
| NACRES |
NA.41
|
| General description【一般描述】 |
Laminins are basement membrane, extracellular matrix glycoproteins that are composed of alpha, beta and gamma heterotrimeric chains. Different combinations of five alpha chains, three beta chains, and two gamma chains form at least 12 laminin isoforms. Laminin subunit alpha-4 contains the C-terminal G domain, and although implicated in developmental regulation due to expression profiles, the biological function of laminin subunit alpha-4 is yet to be fully understood. Laminis as a whole play an important role in cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. High expression has been observed in adult heart, lung, ovary, small and large intestines, placenta, and liver, with lower levels observed in skeletal muscle, kidney, pancreas, testis, prostate, and rain.
|
| Immunogen【免疫原】 |
Recombinant protein corresponding to human Laminin subunit alpha-4.
|
| Application【应用】 |
Research Category
Cell Structure Anti-Laminin subunit alpha-4 Antibody, clone 3H2 detects level of Laminin subunit alpha-4 & has been published & validated for use in WB, IH, IP, ELISA. Research Sub Category ECM Proteins Immunohistochemistry Analysis: A 1:500 dilution from a previous lot detected Laminin subunit alpha-4 in basal cell carcinoma tissue. ELISA Analysis: A previous lot was used by an independent laboratory in ELISA. (Wondimu, Z., et al. (2004). Blood. 104(6):1859-1866.) Immunoprecipitation Analysis: A previous lot was used by an independent laboratory in IP. (Wondimu, Z., et al. (2004). Blood. 104(6):1859-1866.) |
| Quality【质量】 |
Evaluated by Western Blot in human serum tissue lysate under non-reduced conditions.
Western Blot Analysis: A 1:50,000 dilution of this antibody detected Laminin subunit alpha-4 in 10 ?g of human serum tissue lysate (non-reduced conditions). |
| Physical form【外形】 |
Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Format: Purified Protein G Purified |
| Analysis Note【分析说明】 |
Control
Human serum tissue lysate (non-reduced) |
半岛bd体育手机客户端 性质
| Quality Level【质量水平】 |
100
|
| biological source【生物来源】 |
mouse
|
| antibody form【抗体形式】 |
purified antibody
|
| antibody product type |
primary antibodies
|
| clone【克隆】 |
3H2, monoclonal
|
| species reactivity |
human
|
| technique(s) |
ELISA: suitable
immunohistochemistry: suitable immunoprecipitation (IP): suitable western blot: suitable |
| isotype【同位素/亚型】 |
IgG1κ
|
| NCBI accession no.【NCBI登记号】 |
NP_001098676
|
| UniProt accession no.【UniProt登记号】 |
Q16363
|
| shipped in【运输】 |
wet ice
|
| Gene Information |
human ... LAMA4(3910)
|
半岛bd体育手机客户端 说明
| Target description【目标描述】 |
~202 kDa observed under non-reduced conditions.
|
| Storage and Stability【储存及稳定性】 |
Stable for 1 year at 2-8°C from date of receipt.
|
| Disclaimer【免责声明】 |
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
|
安全信息
| Storage Class Code【储存分类代码】 |
12 - Non Combustible Liquids
|
| WGK |
WGK 1
|
