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Thiol-dPEG®12-acid
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别名
Thiol-dPEG®12-acid
CT(PEG)12
Carboxy-PEG-Thiol
Thiol-PEG12-acid
Carboxy-PEG12-Thiol
HS-PEG12-COOH
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C27H54O14S |
| Molecular weight | 634.77 |
| MDL number | MFCD21363238 |
| Features and Benefits【特点和优势】 | Thiol-dPEG12-acid is a single molecular weight, discrete-length polyethylene glycol (dPEG) crosslinking PEGylation reagent. One end of the crosslinker terminates in a sulfhydryl (thiol) group. Propionic acid terminates the opposite end. The thiol end of the molecule forms dative bonds with gold. Moreover, it forms thioether bonds with maleimide and bromoacetate groups and disulfide bonds with other sulfhydryl groups. The propionic acid group reacts with amines to form amide bonds. Alternatively, if it is left unreacted, the propionic acid group provides a negative charge to the conjugated molecule or modified surface. The monodispersed dPEG spacer is 39 atoms (46.8 Å) long. |
| Legal Information【法律信息】 | Products Protected under U.S. Patent #s 7,888,536 & 8,637,711 and European Patent #s 1,594,440 & 2,750,681 dPEG is a registered trademark of Quanta BioDesign |
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性质
| Assay【测定】 | >95% (HPLC) |
| form【形式】 | solid or viscous liquid |
| reaction suitability | reaction type: Pegylations |
| polymer architecture【聚合物结构设计】 | shape: linear functionality: heterobifunctional |
| shipped in【运输】 | ambient |
| storage temp.【储存温度】 | −20℃ |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
