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人半乳凝素-8 ELISA试剂盒
Human Galectin-8 ELISA Kit
| 半岛bd体育手机客户端 编号： | 4119321 |
| 规格： | for cell culture supernatants, plasma, and serum samples |
| 包装规格： | 96 WELLS |
| 半岛bd体育手机客户端 类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
半岛bd体育手机客户端 别名
人半乳凝素-8 ELISA试剂盒
Human Galectin-8 ELISA Kit
基本信息
| NACRES |
NA.32
|
| General description【一般描述】 |
This ELISA antibody pair detects Human Galectin-8 (LGALS8)
|
| Application【应用】 |
For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details. |
| Biochem/physiol Actions【生化/生理作用】 |
Galectin-8 (Gal-8) is a member of “tandem-repeat” galectin family, possesses two carbohydrate binding domains linked by a short peptide. The short peptide accounts for Gal-8 cell adhesion and downstream signalling. Tumor cells, as well as normal tissues, express Gal-8. The expression level of Gal-8 is higher in multiple myeloma conditions and enhances adhesion to vascular endothelium. Galectin-8 binds to integrin selectively and inhibits cell adhesion and promotes apoptosis. Gal-8 interacts with integrin alpha and regulates neutrophil adhesion to endothelial cells and migration. Gal-8 ligand binds to cluster of differentiation 44 (CD44) and causes an inflammatory response in rheumatoid arthritis. Overexpression of Gal-8 plays a key role in metastasis of prostate cancer and cell survival by causing rearrangement of the cytoskeleton and E-cadherin expression.
|
| Other Notes【其他说明】 |
A sample Certificate of Analysis is available for this product. Please type the word
samplein the text box provided for lot number.
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半岛bd体育手机客户端 性质
| species reactivity |
human
|
| packaging【包装】 |
kit of 96 wells (12 strips x 8 wells)
|
| technique(s) |
ELISA: suitable
|
| input |
sample type cell culture supernatant(s)
sample type plasma sample type serum sample(s) |
| assay range |
inter-assay cv: <12%
intra-assay cv: <10% sensitivity: 0.16 ng/ml |
| Detection Method |
colorimetric
|
| shipped in【运输】 |
wet ice
|
| storage temp.【储存温度】 |
?20℃
|
| Gene Information |
human ... LGALS8(3964)
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安全信息
| Pictograms【象形图】 |
GHS05
|
| Signal word【警示用语：】 |
Warning
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| Hazard Statements |
H290
|
| Precautionary Statements |
P234 - P390
|
| Hazard Classifications【危险分类】 |
Met. Corr. 1
|
| Storage Class Code【储存分类代码】 |
8A - Combustible, corrosive hazardous materials
|
| WGK |
WGK 3
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