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Cefiderocol
| 半岛bd体育手机客户端 编号： | 4117258 |
| CAS NO： | 1225208-94-5 |
| 包装规格： | 2 mg |
| 半岛bd体育手机客户端 类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
半岛bd体育手机客户端 别名
1225208-94-5
Cefiderocol
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 |
C
30H
34ClN
7O
10S
2
|
| Molecular weight |
752.21
|
| MDL number |
MFCD30533432
|
| General description【一般描述】 |
Cefiderocol is a novel injectable siderophore cephalosporin, which was formerly known as S-649266.(1)(3) It has a catechol-type siderophore and cephalosporin core and side chains.(1) Cefiderocol has structural similarity with both ceftazidime and cefepime, besides the chlorocatechol group on the end of the C-3 chain.(2)
|
| Biochem/physiol Actions【生化/生理作用】 |
Cefiderocol has strong antimicrobial properties especially against a wide spectrum of Gram-negative pathogens.(1)(3) Due to its siderophore core, it is also a natural iron-chelator, which adds to its antibacterial activities.(1)
|
半岛bd体育手机客户端 性质
| Quality Level【质量水平】 |
100
|
| Assay【测定】 |
≥95% (HPLC)
|
| antibiotic activity spectrum【抗生素抗菌谱】 |
Gram-negative bacteria
|
| Mode of action【作用机制】 |
protein synthesis | inhibits
|
| storage temp.【储存温度】 |
?20℃
|
| SMILES string |
NC1=NC(/C(C(N[C@@H]2C(N3[C@@H]2SCC(C[N+]4(CCCC4)CCNC(C5=CC=C(O)C(O)=C5Cl)=O)=C3C([O-])=O)=O)=O)=N/OC(C(O)=O)(C)C)=CS1
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