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CD24 (mouse): FC (human)
| 半岛bd体育手机客户端 编号： | 4117184 |
| 规格： | recombinant, expressed in HEK 293 cells, >90% (SDS-PAGE) |
| 包装规格： | 50 μG |
| 半岛bd体育手机客户端 类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
半岛bd体育手机客户端 别名
CD24 (mouse): FC (human)
X62 Heat stable antigen (HSA)
NaMN adenylyltransferase 1
M1/69-J11D heat stable antigen
Nectadrin
基本信息
| NACRES |
NA.32
|
| General description【一般描述】 |
CD24 is a highly glycosylated protein expressed as glycosyl-phosphatidyl-inositol (GPI) anchored molecule. Widely expressed, mainly on T cells, B cells and is upregulated in numerous types of cancers. It has costimulatory activity for antigen specific T cell responses. Polymorphisms of human CD24 are associated with several autoimmune diseases. Recently a new role as negative regulator of the immune response has been reported. CD24-deficient mice are more sensitive to inflammatory responses. CD24 together with the membrane protein SIGLEC interacts with danger-associated molecular patterns (DAMPs), such as HMGB1, HSP90 or HSP70. CD24/SIGLEC complex may differentially regulate the host response to DAMPs and PAMPs (pathogen-associated molecular patterns).
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| Physical form【外形】 |
Lyophilized from PBS.
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| Reconstitution【重悬】 |
Reconstitute with 50 μL deionized water.
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| Other Notes【其他说明】 |
Mouse CD24 (aa 27-52) is fused at the C-terminus to the Fc portion of human IgG1.
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半岛bd体育手机客户端 性质
| biological source【生物来源】 |
mouse
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| recombinant【重组】 |
expressed in HEK 293 cells
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| Assay【测定】 |
>90% (SDS-PAGE)
|
| form【形式】 |
lyophilized
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| mol wt【分子量】 |
~50 kDa by SDS-PAGE
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| packaging【包装】 |
pkg of 50 μg
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| impurities【杂质】 |
<0.06 EU/μg endotoxin, tested
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| UniProt accession no.【UniProt登记号】 |
P24807
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| shipped in【运输】 |
wet ice
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| storage temp.【储存温度】 |
?20℃
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| Gene Information |
mouse ... CD24(100133941)
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安全信息
| Storage Class Code【储存分类代码】 |
12 - Non Combustible Liquids
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| WGK |
WGK 3
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