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Anti-Phospho-CSF1R-Y708 antibody produced in rabbit

半岛bd体育手机客户端 编号:4112301
半岛bd体育手机客户端 类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
半岛bd体育手机客户端 价格
半岛bd体育手机客户端 编号包装单位单价(元)国内现货国外库存询价单
41123015400
半岛bd体育手机客户端 性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
100
antibody product type
primary antibodies
clone【克隆】
polyclonal
form【形式】
liquid
species reactivity
rat, human, mouse
concentration【浓度】
2.1 mg/mL
technique(s)
immunohistochemistry: 1:50-1:200
western blot: 1:500-1:2000
UniProt accession no.【UniProt登记号】
P07333
shipped in【运输】
wet ice
storage temp.【储存温度】
−20℃
Gene Information
human ... CSF1R(1436)
基本信息
General description【一般描述】
The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. Alternative splicing results in multiple transcript variants. Expression of a splice variant from an LTR promoter has been found in Hodgkin lymphoma (HL), HL cell lines and anaplastic large cell lymphoma.
Immunogen【免疫原】
A synthetic phosphorylated peptide around Y708 of human CSF1R (NP_005202.2).
Physical form【外形】
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
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