Anti-Haptoglobin (HP) antibody produced in rabbit

rabbit

100

primary antibodies

monoclonal

liquid

mouse, rat, human

0.4 mg/mL

immunohistochemistry: 1:50-1:200
western blot: 1:500-1:2000

P00738

wet ice

−20℃

human ... HP(3240)

This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria. The protein encoded also exhibits antimicrobial activity against bacteria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2014]

A synthesized peptide derived from human Haptoglobin (HP) (HP)

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.