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Anti- KEAP1 antibody produced in rabbit
半岛bd体育手机客户端 性质
| biological source【生物来源】 |
rabbit
|
| Quality Level【质量水平】 |
100
|
| antibody product type |
primary antibodies
|
| clone【克隆】 |
polyclonal
|
| form【形式】 |
liquid
|
| species reactivity |
mouse, human, rat
|
| concentration【浓度】 |
1.51 mg/mL
|
| technique(s) |
immunohistochemistry: 1:50-1:200
western blot: 1:500-1:2000 |
| UniProt accession no.【UniProt登记号】 |
Q14145
|
| shipped in【运输】 |
wet ice
|
| storage temp.【储存温度】 |
?20℃
|
| Gene Information |
human ... KEAP1(9817)
|
基本信息
| General description【一般描述】 |
This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.
|
| Immunogen【免疫原】 |
A synthetic peptide of human KEAP1.
|
| Physical form【外形】 |
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
|
