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中心 > Anti-Ly-6G (Gr-1) Antibody (mouse), PE-Cy7, clone RB6-8C5
Anti-Ly-6G (Gr-1) Antibody (mouse), PE-Cy7, clone RB6-8C5
| 半岛bd体育手机客户端 编号： | 4102468 |
| 规格： | clone RB6-8C5, 0.2 mg/mL, from rat |
| 包装规格： | 100 μG |
| 半岛bd体育手机客户端 类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
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别名
Anti-Ly-6G (Gr-1) Antibody (mouse), PE-Cy7, clone RB6-8C5
Lymphocyte antigen 6G, Ly-6G, Ly-6G.1
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | The RB6-8C5 antibody binds to mouse Ly-6G, commonly known as Gr-1, a member of the Ly-6 superfamily of GPI-anchored cell surface proteins with roles in cell signaling and cell adhesion. Gr-1 is differentially expressed during development and maturation of cells in the myeloid lineage and is expression at varying stages and levels on monocytes, macrophages, granulocytes, and peripheral neutrophils. In the mouse, the RB6-8C5 antibody is typically used in combination with the macrophage labeling antibody M1/70 (Anti-CD11b) for phenotypic analysis of monocytes, macrophages and granulocytes.Note: The RB6-8C5 antibody has been reported to cross-react with Ly-6C on cells expressing this antigen (Fleming et al. 1993. J. Immunol. 151:2399-2408 and Sasmono et al. 2007. J. Leukoc. Biol. 82: 111-123) and has been cited in the literature for identification of Ly-6G/Ly-6C. Other reports sµggest that this antibody is specific for Ly-6G, without cross-reactivity for Ly-6C (Nagendra S. and Schlueter AJ. 2003. Cytometry A, 58(2): 195-200. This rat monoclonal antibody Anti-Ly-6G (Gr-1) (mouse), PE-Cy7, clone RB6-8C5 validated for use in IHC, Flow Cytometry & IP for the detection of Ly-6G (Gr-1). |
| Quality【质量】 | The monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation. Flow Cytometry Analysis: 0.25 µg of this antibody detected Ly-6G (Gr-1) in one million C57Bl/6 bone marrow cells. |
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性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | rat |
| conjugate【偶联物】 | PE-Cy7 |
| antibody form【抗体形式】 | purified antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | RB6-8C5, monoclonal |
| species reactivity | mouse |
| concentration【浓度】 | 0.2 mg/mL |
| technique(s) | flow cytometry: suitable immunohistochemistry: suitable immunoprecipitation (IP): suitable |
| isotype【同位素/亚型】 | IgG2bκ |
| UniProt accession no.【UniProt登记号】 | P35461 |
| shipped in【运输】 | wet ice |
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说明
| 【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | nwg |
