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Ligstroside
半岛bd体育手机客户端 编号: | 4073852 |
规格: | Nitric oxide inhibitor, ≥95% |
CAS NO: | 35897-92-8 |
包装规格: | 1 MG |
半岛bd体育手机客户端 类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
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别名
35897-92-8
Ligstroside
Ligustroside
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C25H32O12 |
Molecular weight | 524.51 |
Biochem/physiol Actions【生化/生理作用】 | Ligstroside is a natural product derived from leaves of Olea europaea. Ligstroside displays several potentially beneficial anti-inflammatory properties by exhibiting selective inhibition effect on COX-1 enzyme of arachidonate cascade metabolism. Ligstroside generates a reduction of the PGE2 (prostaglandin E2) levels in activated mouse macrophage (IC50 = 48.53 μM) and also reduction of the TXB2 (thromboxane B2) levels in human platelets (IC50 = 122.63 μM). Moreover, Ligstroside exhibits inhibition activity of NO production in LPS-activated RAW264.7 macrophages (17.8% at 30 μM and 40.7% at 100 μM) without any cytotoxic effect in these cells., Additionally, Ligstroside exhibits in vitro antiviral activity against parainfluenza type 3 virus (IC50 = 15.6 μM). |
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性质
Quality Level【质量水平】 | 100 |
Assay【测定】 | ≥95% |
form【形式】 | lyophilized powder |
solubility【溶解性】 | DMSO: ≥10 mg/mL (19 mM) methanol: ≥10 mg/mL |
storage temp.【储存温度】 | −20℃ |
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说明
Storage and Stability【储存及稳定性】 | Hygroscopic; store in dry place with desiccant |
安全信息
Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
WGK | WGK 3 |