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N-C12-desoxymethylsphinganine
| 半岛bd体育手机客户端 编号： | 4072606 |
| 规格： | N-lauroyl-1-desoxymethylsphinganine (m17:0/12:0), powder |
| CAS NO： | 1246298-41-8 |
| 包装规格： | 1 MG |
| 半岛bd体育手机客户端 类别： | 进口试剂 |
| 品牌： | Avanti |
| 优惠价： | 立即咨询 |
半岛bd体育手机客户端 别名
1246298-41-8
N-C12-desoxymethylsphinganine
N-dodecanoyl-1-desoxymethylsphinganine (m17:0/12:0); N-C12-1-desoxyMeDHCer; 110959
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 |
C
29H
59NO
2
|
| Molecular weight |
453.78
|
| General description【一般描述】 |
N-C12-desoxymethylsphinganine commonly referred to as 1-deoxydihydroceramide (1-deoxyDHCer), is the
N-acylated form of 1-deoxysphinganine, a potent inhibitor of sphingolipid metabolism.
Commonly referred to as 1-desoxymethyldihydroceramide (1-desoxyMeDHCer), this product is the N-acylated form of 1-desoxymethylsphinganine, a potent inhibitor of sphingolipid metabolism. The biological activity of 1-desoxyMeDHCer is not clearly understood at this time. |
| Biochem/physiol Actions【生化/生理作用】 |
Ceramide synthases (CerS) catalyzes the acylation of sphingoid bases using fatty acyl-CoA and its inhibition results in decrease of desoxymethylsphinganine (
N-acylsphinganines (dihydroceramides)) levels and accumulation of sphinganine (Sa). Dihydroceramides (DHCer) are intermediates of ceramide biosynthesis.
|
半岛bd体育手机客户端 性质
| Assay【测定】 |
>99% (TLC)
|
| form【形式】 |
powder
|
| manufacturer/tradename |
Avanti Polar Lipids 860461P
|
| shipped in【运输】 |
dry ice
|
| storage temp.【储存温度】 |
?20℃
|
| packaging【包装】 |
5 mL Amber Glass Screw Cap Vial (860461P-1mg)
|
安全信息
| Storage Class Code【储存分类代码】 |
13 - Non Combustible Solids
|
| WGK |
WGK 3
|
