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Anti-P2RY14 / P2Y14 antibody produced in rabbit
| 半岛bd体育手机客户端 编号： | 3382008 |
| 规格： | affinity isolated antibody |
| 包装规格： | 50 μG |
| 半岛bd体育手机客户端 类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
半岛bd体育手机客户端 别名
Anti-P2RY14 / P2Y14 antibody produced in rabbit
p2Y(14) receptor
P2Y purinoceptor 14
UDP-glucose receptor
G-protein coupled receptor 105
P2RY14
p2Y14 receptor
半岛bd体育手机客户端 性质
| biological source【生物来源】 |
rabbit
|
| Quality Level【质量水平】 |
100
|
| conjugate【偶联物】 |
unconjugated
|
| antibody form【抗体形式】 |
affinity isolated antibody
|
| antibody product type |
primary antibodies
|
| clone【克隆】 |
polyclonal
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| form【形式】 |
buffered aqueous solution
|
| species reactivity |
human
|
| technique(s) |
immunocytochemistry: 5-10 μg/mL
immunohistochemistry: 4 μg/mL |
| UniProt accession no.【UniProt登记号】 |
Q15391
|
| shipped in【运输】 |
dry ice
|
| storage temp.【储存温度】 |
?20℃
|
| Gene Information |
human ... P2RY14(9934)
|
基本信息
| General description【一般描述】 |
Caspases mediate essential key proteolytic events in inflammatory cascades and the apoptotic cell death pathway. Caspase 12 is involved in the apoptosis triggered by a stress on the endoplasmic reticulum. Caspase-12 is co-localized to the ER with several proteins that are involved in Alzheimer′s disease including gamma-secretase presenilin and beta-amyloid precursor protein (APP). Caspase-12 mediates cytotoxicity induced by amyloid-beta. Caspase 12 activation results in cell death in the absence of the cytochrome c-dependent pathway. Recently caspase-12 has been suggested to affect signaling pathways linking some G-protein coupled receptors to alphaIIbbeta3 activation. Caspase-12 is ubiquitously expressed in mouse tissues.
|
| Immunogen【免疫原】 |
Synthetic 20 amino acid peptide from C-terminus of human P2RY14 / P2Y14. Percent identity with other species by BLAST analysis: Human (100%); Monkey (95%).
|
| Features and Benefits【特点和优势】 |
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
|
| Physical form【外形】 |
Supplied at 1 mg/ml
Solution in phosphate-buffered saline containing less than 0.1% sodium azide. |
半岛bd体育手机客户端 说明
| Disclaimer【免责声明】 |
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
|
安全信息
| Storage Class Code【储存分类代码】 |
12 - Non Combustible Liquids
|
