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Anti-GLP1R antibody produced in rabbit
| 半岛bd体育手机客户端 编号： | 3364987 |
| 规格： | affinity isolated antibody |
| 包装规格： | 100 μG |
| 半岛bd体育手机客户端 类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
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别名
Anti-GLP1R antibody produced in rabbit
GLP1R
GLP-1R
GLP-1-R
GLP-1 receptor
Glucagon-like peptide 1 receptor
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | Glucagon-like peptide 1 receptor (GLP1R) protein belongs to the class B G protein-coupled receptor (GPCR) secretin family. This classic seven-transmembrane protein is abundantly expressed in the cardiovascular system. The GLP1R gene is located on the human chromosome 6p21. Anti-GLP1R Antibody detects endogenous levels of total GLP1R protein. Anti-GLP1R Antibody detects endogenous levels of total GLP1R protein. |
| Immunogen【免疫原】 | The antiserum was produced against synthesized peptide derived from human GLP1R. Immunogen Range: 101-150 |
| Application【应用】 | Anti-GLP1R antibody produced in rabbit has been used in immunofluorescence staining. |
| Biochem/physiol Actions【生化/生理作用】 | Glucagon-like peptide 1 receptor (GLP1R) protein participates in the activation of protein kinase A (PKA), phosphoinositide 3-kinase (PI3K), MEK1/2, and endothelial nitric oxide synthase (eNOS) pathways. Hence, it plays a key role in apoptosis reduction, improved energy metabolism, decreased inflammation in myocardial cells, and vasodilation in myocardial arteries. The large N-terminal extracellular domain of GLP1R participates in ligand binding. Alterations in the GLP1R gene might increase the risk of coronary artery disease (CAD). |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
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性质
| biological source【生物来源】 | rabbit |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen 53 kDa |
| species reactivity | mouse, human |
| concentration【浓度】 | ~1 mg/mL |
| technique(s) | ELISA: 1:5000 immunofluorescence: 1:100-1:500 |
| NCBI accession no.【NCBI登记号】 | P43220 |
| UniProt accession no.【UniProt登记号】 | P43220 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... GLP1R(2740) |
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说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | nwg |
