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Anti-FNTB (N-term) antibody produced in rabbit
| 半岛bd体育手机客户端 编号： | 3362968 |
| 规格： | IgG fraction of antiserum, buffered aqueous solution |
| 包装规格： | 100 μG |
| 半岛bd体育手机客户端 类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
半岛bd体育手机客户端 别名
Anti-FNTB (N-term) antibody produced in rabbit
Anti-EC 2.5.1.58
Anti-FTase-β
CAAX farnesyltransferase subunit β
Anti-Protein farnesyltransferase subunit β
RAS proteins prenyltransferase β
基本信息
| NACRES |
NA.41
|
| General description【一般描述】 |
Eukaryotic cells contain 3 different types of prenyltransferases that attach either a farnesyl group (15 carbons) or a geranylgeranyl group (20 carbons) in thioether linkage to C-terminal cysteine residues in a variety of proteins. These posttranslational modifications provide a mechanism for membrane localization of proteins that lack a transmembrane domain. CAAX farnesyltransferase (FTase) attaches a farnesyl group from farnesyl pyrophosphate to cysteine residues at the fourth position from the C terminus of proteins that end in the CAAX box, where C is cysteine, A is usually but not always an aliphatic amino acid, and X is typically methionine or serine. This enzyme has the ability to farnesylate peptides as short as 4 residues in length that conform to the CAAX consensus sequence. The gene for the beta subunit of CAAX farnesyltransferase (FNTB) has been pinpointed to 14q23-q24 by Southern blot hybridization and PCR analyses of panels of human/Chinese hamster somatic cell hybrid lines and by fluorescence chromosomal in situ hybridization.
|
| Immunogen【免疫原】 |
FNTB (NP_002019, )
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human FNTB. |
| Physical form【外形】 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
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半岛bd体育手机客户端 性质
| biological source【生物来源】 |
rabbit
|
| conjugate【偶联物】 |
unconjugated
|
| antibody form【抗体形式】 |
IgG fraction of antiserum
|
| antibody product type |
primary antibodies
|
| clone【克隆】 |
polyclonal
|
| form【形式】 |
buffered aqueous solution
|
| species reactivity |
human
|
| technique(s) |
immunohistochemistry: 1:50-1:100
indirect ELISA: 1:1000 western blot: 1:100-1:500 |
| NCBI accession no.【NCBI登记号】 |
NP_002019
|
| UniProt accession no.【UniProt登记号】 |
P49356
|
| shipped in【运输】 |
dry ice
|
| storage temp.【储存温度】 |
?20℃
|
| Gene Information |
human ... FNTB(2342)
|
安全信息
| Storage Class Code【储存分类代码】 |
12 - Non Combustible Liquids
|
| WGK |
nwg
|
