您的位置：首页 > 半岛bd体育手机客户端 中心 > Anti-FCER1A antibody produced in rabbit
Anti-FCER1A antibody produced in rabbit
| 半岛bd体育手机客户端 编号： | 3362117 |
| 规格： | purified immunoglobulin, buffered aqueous solution |
| 包装规格： | 100UG |
| 半岛bd体育手机客户端 类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
半岛bd体育手机客户端 别名
Anti-FCER1A antibody produced in rabbit
FcERI
FCE1A
基本信息
| NACRES |
NA.41
|
| General description【一般描述】 |
The IgE receptor plays a central role in allergic disease, coupling allergen and mast cell to initiate the inflammatory and immediate hypersensitivity responses that are characteristic of disorders such as hay fever and asthma. The allergic response occurs when 2 or more high-affinity IgE receptors are crosslinked via IgE molecules that in turn are bound to an allergen (antigen) molecule. A perturbation occurs that brings about the release of histamine and proteases from the granules in the cytoplasm of the mast cell and leads to the synthesis of prostaglandins and leukotrienes--potent effectors of the hypersensitivity response. The IgE receptor consists of 3 subunits: alpha, beta (MIM 147138), and gamma (MIM 147139); only the alpha subunit is glycosylated.[supplied by OMIM
|
| Immunogen【免疫原】 |
FCER1A (NP_001992.1, 1 a.a. ~ 257 a.a) full-length human protein.
Sequence MAPAMESPTLLCVALLFFAPDGVLAVPQKPKVSLNPPWNRIFKGENVTLTCNGNNFFEVSSTKWFHNGSLSEETNSSLNIVNAKFEDSGEYKCQHQQVNESEPVYLEVFSDWLLLQASAEVVMEGQPLFLRCHGWRNWDVYKVIYYKDGEALKYWYENHNISITNATVEDSGTYYCTGKVWQLDYESEPLNITVIKAPREKYWLQFFIPLLVVILFAVDTGLFISTQQQVTFLLKIKRTRKGFRLLNPHPKPNPKNN |
| Physical form【外形】 |
Solution in phosphate buffered saline, pH 7.4
|
半岛bd体育手机客户端 性质
| biological source【生物来源】 |
rabbit
|
| Quality Level【质量水平】 |
100
|
| conjugate【偶联物】 |
unconjugated
|
| antibody form【抗体形式】 |
purified immunoglobulin
|
| antibody product type |
primary antibodies
|
| clone【克隆】 |
polyclonal
|
| form【形式】 |
buffered aqueous solution
|
| mol wt【分子量】 |
antigen 29.6 kDa
|
| species reactivity |
human
|
| technique(s) |
western blot: 1 μg/mL
|
| NCBI accession no.【NCBI登记号】 |
NM_002001.2
|
| UniProt accession no.【UniProt登记号】 |
P12319
|
| shipped in【运输】 |
dry ice
|
| storage temp.【储存温度】 |
?20℃
|
| Gene Information |
human ... FCER1A(2205)
|
安全信息
| Storage Class Code【储存分类代码】 |
12 - Non Combustible Liquids
|
| WGK |
WGK 3
|
