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Anti-COX10 antibody produced in mouse
| 半岛bd体育手机客户端 编号： | 3354830 |
| 规格： | purified immunoglobulin, buffered aqueous solution |
| 包装规格： | 50 μG |
| 半岛bd体育手机客户端 类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
基本信息
| NACRES |
NA.41
|
| General description【一般描述】 |
Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes heme A:farnesyltransferase, which is not a structural subunit but required for the expression of functional COX and functions in the maturation of the heme A prosthetic group of COX. This protein is predicted to contain 7-9 transmembrane domains localized in the mitochondrial inner membrane. A gene mutation, which results in the substitution of a lysine for an asparagine (N204K), is identified to be responsible for cytochrome c oxidase deficiency. In addition, this gene is disrupted in patients with CMT1A (Charcot-Marie-Tooth type 1A) duplication and with HNPP (hereditary neuropathy with liability to pressure palsies) deletion. (provided by RefSeq)
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| Immunogen【免疫原】 |
COX10 (AAH06394, 1 a.a. ~ 443 a.a) full-length human protein.
Sequence MAASPHTLSSRLLTGCVGGSVWYLERRTIQDSPHKFLHLLRNVNKQWITFQHFSFLKRMYVTQLNRSHNQQVRPKPEPVASPFLEKTSSGQAKAEIYEMRPLSPPSLSLSRKPNEKELIELEPDSVIEDSIDVGKETKEEKRWKEMKLQVYDLPGILAQLSKIKLTALVVSTTAAGFALAPGPFDWPCFLLTSVGTGLASCAANSINQFFEVPFDSNMNRTKNRPLVRGQISPLLAVSFATCCAVPGVAILTLGVNPLTGALGLFNIFLYTCCYTPLKRISIANTWVGAVVGAIPPVMGWTAATGSLDAGAFLLGGILYSWQFPHFNALSWGLREDYSRGGYCMMSVTHPGLCRRVALRHCLALLVLSAAAPVLDITTWTFPIMALPINAYISYLGFRFYVDADRRSSRRLFFCSLWHLPLLLLLMLTCKRPSGGGDAGPPPS |
| Physical form【外形】 |
Solution in phosphate buffered saline, pH 7.4
|
半岛bd体育手机客户端 性质
| Quality Level【质量水平】 |
100
|
| biological source【生物来源】 |
mouse
|
| conjugate【偶联物】 |
unconjugated
|
| antibody form【抗体形式】 |
purified immunoglobulin
|
| antibody product type |
primary antibodies
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| clone【克隆】 |
polyclonal
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| form【形式】 |
buffered aqueous solution
|
| mol wt【分子量】 |
antigen ~48.73 kDa
|
| species reactivity |
human
|
| technique(s) |
western blot: 1 μg/mL
|
| NCBI accession no.【NCBI登记号】 |
BC006394
|
| UniProt accession no.【UniProt登记号】 |
Q12887
|
| shipped in【运输】 |
dry ice
|
| storage temp.【储存温度】 |
?20℃
|
| Gene Information |
human ... COX10(1352)
|
安全信息
| Storage Class Code【储存分类代码】 |
13 - Non Combustible Solids
|
| WGK |
WGK 1
|
