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Anti-CCR5 antibody produced in mouse
| 半岛bd体育手机客户端 编号： | 3351859 |
| 规格： | purified immunoglobulin, buffered aqueous solution |
| 包装规格： | 50 μG |
| 半岛bd体育手机客户端 类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
半岛bd体育手机客户端 别名
Anti-CCR5 antibody produced in mouse
CMKBR5
CD195
CC-CKR-5
IDDM22
CCCKR5
CKR-5
CKR5
半岛bd体育手机客户端 性质
| biological source【生物来源】 |
mouse
|
| conjugate【偶联物】 |
unconjugated
|
| antibody form【抗体形式】 |
purified immunoglobulin
|
| antibody product type |
primary antibodies
|
| clone【克隆】 |
polyclonal
|
| form【形式】 |
buffered aqueous solution
|
| mol wt【分子量】 |
antigen ~40.5 kDa
|
| species reactivity |
human
|
| technique(s) |
flow cytometry: suitable
western blot: 1 μg/mL |
| NCBI accession no.【NCBI登记号】 |
NM_000579
|
| UniProt accession no.【UniProt登记号】 |
P51681
|
| shipped in【运输】 |
dry ice
|
| storage temp.【储存温度】 |
?20℃
|
| Gene Information |
human ... CCR5(1234)
|
基本信息
| General description【一般描述】 |
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Two transcript variants encoding the same protein have been found for this gene. (provided by RefSeq)
|
| Immunogen【免疫原】 |
CCR5 (XP_001125981.1, 1 a.a. ~ 352 a.a) full-length human protein.
Sequence MDYQVSSPIYDINYYTSEPCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILINCKRLKSMTDIYLLNLAISDLFFLLTVPFWAHYAAAQWDFGNTMCQLLTGLYFIGFFSGIFFIILLTIDRYLAVVHAVFALKARTVTFGVVTSVITWVVAVFASLPGIIFTRSQKEGLHYTCSSHFPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRCRNEKKRHRAVRLIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFVGEKFRNYLLVFFQKHIAKRFCKCCSIFQQEAPERASSVYTRSTGEQEISVGL |
| Physical form【外形】 |
Solution in phosphate buffered saline, pH 7.4
|
半岛bd体育手机客户端 说明
| Disclaimer【免责声明】 |
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
|
安全信息
| Storage Class Code【储存分类代码】 |
13 - Non Combustible Solids
|
| WGK |
WGK 1
|
