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Anti-CA3 antibody produced in rabbit
| 半岛bd体育手机客户端 编号： | 3350354 |
| 规格： | affinity isolated antibody |
| 包装规格： | 100 μG |
| 半岛bd体育手机客户端 类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
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别名
Anti-CA3 antibody produced in rabbit
Carbonic anhydrase 3
Carbonate dehydratase III
CA-III
Carbonic anhydrase III
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | Anti-CA3 Antibody detects endogenous levels of total CA3 protein. Carbonic anhydrase III (CA3) is a member of a multi-gene CA family that encodes carbonic anhydrase isozymes namely Car3 and CAIII. The expression of isozymes has been shown to abundantly increase during muscle aging and is relatively muscle specific. It exhibits a fibre type-specific expression pattern. |
| Immunogen【免疫原】 | The antiserum was produced against synthesized peptide derived from human CA3. Immunogen Range: 141-190 |
| Application【应用】 | Anti-CA3 antibody produced in rabbit is suitable for indirect ELISA and western blot applications. |
| Biochem/physiol Actions【生化/生理作用】 | Carbonic anhydrase III (CA3) may act as a new biomarker of sarcopenia. Higher CA levels indicate an increased demand of CO2 removal in senescent muscle and the age-related fibre type shifts to slower-contracting muscles during human aging. CA3 is found to be associated with rheumatoid arthritis. It is specifically insufficient in the skeletal muscle of patients suffering from Myasthenia gravis (MG) (an autoimmune disease mainly mediated by antibodies against acetylcholine receptor). CA3 possesses low carbon dioxide hydratase activity, resistance to the CA inhibitor acetazolamide unlike the other members of the CA family. |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
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性质
| biological source【生物来源】 | rabbit |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen 29 kDa |
| species reactivity | human, mouse, rat |
| concentration【浓度】 | ~1 mg/mL |
| technique(s) | ELISA: 1:20000 western blot: 1:500-1:1000 |
| NCBI accession no.【NCBI登记号】 | P07451 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... CAH3(761) |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | nwg |
