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AEG 3482
| 半岛bd体育手机客户端 编号： | 3338653 |
| 规格： | ≥98% (HPLC) |
| CAS NO： | 63735-71-7 |
| 包装规格： | 5 MG |
| 半岛bd体育手机客户端 类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
半岛bd体育手机客户端 别名
63735-71-7
AEG 3482
6-Phenyl-imidazo[2,1-b]-1,3,4-thiadiazole-2-sulfonamide
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 |
C
10H
8N
4O
2S
2
|
| Molecular weight |
280.33
|
| MDL number |
MFCD02064987
|
| PubChem Substance ID【PubChem化学物质编号】 |
329825272
|
| NACRES |
NA.77
|
| Biochem/physiol Actions【生化/生理作用】 |
AEG3284 is a compound that binds to heat shock protein 90 (HSP90), leading to heat shock factor 1 (HSF1) dependent expression of HSP70, an endogenous inhibitor of c-Jun N-terminal kinase (JNK) activity. Treatment of PC12 cells with AEF3284 blocks JNK dependent apoptosis.
AEG 3482 is an imidazothiadiazole sulfonamide of 281 D with an anti-apoptotic property. |
| Features and Benefits【特点和优势】 |
This compound is featured on the MAPKs page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
|
半岛bd体育手机客户端 性质
| Quality Level【质量水平】 |
100
|
| Assay【测定】 |
≥98% (HPLC)
|
| form【形式】 |
powder
|
| color【颜色】 |
faintly yellow to dark yellow
|
| solubility【溶解性】 |
DMSO: ≥15 mg/mL
|
| storage temp.【储存温度】 |
2-8℃
|
| SMILES string |
NS(=O)(=O)c1nn2cc(nc2s1)-c3ccccc3
|
| InChI |
1S/C10H8N4O2S2/c11-18(15,16)10-13-14-6-8(12-9(14)17-10)7-4-2-1-3-5-7/h1-6H,(H2,11,15,16)
|
| InChI key |
MQUYTXDAVCOCMX-UHFFFAOYSA-N
|
| packaging【包装】 |
5, 25 mg in glass bottle
|
安全信息
| Pictograms【象形图】 |
GHS07
|
| Signal word【警示用语：】 |
Warning
|
| Hazard Statements |
H302
|
| Hazard Classifications【危险分类】 |
Acute Tox. 4 Oral
|
| Storage Class Code【储存分类代码】 |
13 - Non Combustible Solids
|
| WGK |
WGK 3
|
