您的位置：首页 > 半岛bd体育手机客户端
中心 > 126433-07-6， Tyrphostin 51
Tyrphostin 51
| 半岛bd体育手机客户端 编号： | 3257618 |
| 规格： | ≥98% |
| CAS NO： | 126433-07-6 |
| 包装规格： | 5 MG，25 MG |
| 半岛bd体育手机客户端 类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
半岛bd体育手机客户端
别名
126433-07-6
Tyrphostin 51
2-Amino-1,1,3-tricyano-4-(3′,4′,5′-trihydroxyphenyl)butadiene
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C13H8N4O3 |
| Molecular weight | 268.23 |
| MDL number | MFCD00133903 |
| PubChem Substance ID【PubChem化学物质编号】 | 24278756 |
| NACRES | NA.77 |
| Application【应用】 | Tyrphostin 51 has been used to study the inhibition of rat hepatic leptin 1. |
| Biochem/physiol Actions【生化/生理作用】 | Tyrphostin 51 is a small molecule inhibitor of epidermal growth factor (EGF) receptor kinase function. This molecule associates with the substrate subsite of the protein tyrosine kinase (PTK) domain,. EGFR tyrosine kinase inhibitor. |
| Features and Benefits【特点和优势】 | This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm. |
| Preparation Note【制备说明】 | 5 mg of Tyrphostin 51 is soluble in 0.1 ml of DMSO and yields a clear, orange to red solution. |
半岛bd体育手机客户端
性质
| Quality Level【质量水平】 | 200 |
| biological source【生物来源】 | synthetic (organic) |
| Assay【测定】 | ≥98% |
| form【形式】 | powder |
| potency【效能】 | 0.8 μM IC50 |
| solubility【溶解性】 | DMSO: soluble 5 mg of Tyrphostin 51 in 0.1 ml of solvent, clear, orange to red |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | NC(\C(=C\c1cc(O)c(O)c(O)c1)C#N)=C(/C#N)C#N |
| InChI | 1S/C13H8N4O3/c14-4-8(12(17)9(5-15)6-16)1-7-2-10(18)13(20)11(19)3-7/h1-3,18-20H,17H2/b8-1+ |
| InChI key | JKNOYWVMHPMBEL-UNXLUWIOSA-N |
| Gene Information | human ... CDK2(1017), EGFR(1956) |
| packaging【包装】 | 5 mg in glass bottle 25 mg in poly bottle |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |
