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Monoclonal Anti-STAT3 antibody produced in mouse
| 半岛bd体育手机客户端 编号： | 3152751 |
| 规格： | clone 4D6, purified immunoglobulin, buffered aqueous solution |
| 包装规格： | 100 μG |
| 半岛bd体育手机客户端 类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
半岛bd体育手机客户端 别名
Monoclonal Anti-STAT3 antibody produced in mouse
Anti-MGC16063
Anti-FLJ20882
Anti-APRF
Anti-signal transducer and activator of transcription 3 (acute-phase response factor)
基本信息
| MDL number |
MFCD01092492
|
| NACRES |
NA.41
|
| General description【一般描述】 |
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Three alternatively spliced transcript variants encoding distinct isoforms have been described. (provided by RefSeq)
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| Immunogen【免疫原】 |
STAT3 (NP_003141, 670 a.a. ~ 769 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence LVYLYPDIPKEEAFGKYCRPESQEHPEADPGAAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNNGEGAEPSAGGQFESLTFDMELTSECATSPM |
| Physical form【外形】 |
Solution in phosphate buffered saline, pH 7.4
|
| Legal Information【法律信息】 |
GenBank is a registered trademark of United States Department of Health and Human Services
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半岛bd体育手机客户端 性质
| Quality Level【质量水平】 |
100
|
| biological source【生物来源】 |
mouse
|
| conjugate【偶联物】 |
unconjugated
|
| antibody form【抗体形式】 |
purified immunoglobulin
|
| antibody product type |
primary antibodies
|
| clone【克隆】 |
4D6, monoclonal
|
| form【形式】 |
buffered aqueous solution
|
| species reactivity |
human
|
| technique(s) |
indirect ELISA: suitable
indirect immunofluorescence: suitable proximity ligation assay: suitable western blot: 1-5 μg/mL |
| isotype【同位素/亚型】 |
IgG1κ
|
| GenBank?accession no. |
NM_003150
|
| UniProt accession no.【UniProt登记号】 |
P40763
|
| shipped in【运输】 |
dry ice
|
| storage temp.【储存温度】 |
?20℃
|
| Gene Information |
human ... STAT3(6774)
|
半岛bd体育手机客户端 说明
| Disclaimer【免责声明】 |
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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安全信息
| Storage Class Code【储存分类代码】 |
12 - Non Combustible Liquids
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| Personal Protective Equipment【个人防护装备】 |
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
|
