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Monoclonal Anti-NMNAT2 antibody produced in mouse
| 半岛bd体育手机客户端 编号： | 3149343 |
| 规格： | clone 2E4, purified immunoglobulin, buffered aqueous solution |
| 包装规格： | 100 μG |
| 半岛bd体育手机客户端 类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
半岛bd体育手机客户端 别名
Monoclonal Anti-NMNAT2 antibody produced in mouse
Anti-C1orf15
Anti-nicotinamide nucleotide adenylyltransferase 2
Nmnat2 Antibody-Monoclonal Anti-NMNAT2 antibody produced in mouse
Anti-KIAA0479
Anti-MGC2756
Nmnat2 Antibody
Anti-PNAT2
基本信息
| NACRES |
NA.41
|
| General description【一般描述】 |
This gene product belongs to the nicotinamide mononucleotide adenylyltransferase (NMNAT) enzyme family, members of which catalyze an essential step in NAD (NADP) biosynthetic pathway. Unlike the other human family member, which is localized to the nucleus, and is ubiquitously expressed; this enzyme is cytoplasmic, and is predominantly expressed in the brain. Two transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq)
NMNAT2 (nicotinamide nucleotide adenylyltransferase 2) is a rate limiting enzyme that is located on human chromosome 1q25. It is expressed in the brain. Nmnat2 is located to vesicular structures. |
| Immunogen【免疫原】 |
NMNAT2 (NP_055854, 208 a.a. ~ 307 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence CIPGLWNEADMEVIVGDFGIVVVPRDAADTDRIMNHSSILRKYKNNIMVVKDDINHPMSVVSSTKSRLALQHGDGHVVDYLSQPVIDYILKSQLYINASG |
| Application【应用】 |
Monoclonal Anti-NMNAT2 antibody has been used in immunoblotting.
|
| Biochem/physiol Actions【生化/生理作用】 |
NMNAT2 (nicotinamide nucleotide adenylyltransferase 2) plays a major role in cancer suppression. It may induce multiplication and prevent apoptosis in CRC (colorectal cancer) cells. NMNAT2 participates in energy metabolism. This protein helps to postpone axon degeneration.
|
| Physical form【外形】 |
Solution in phosphate buffered saline, pH 7.4
|
| Legal Information【法律信息】 |
GenBank is a registered trademark of United States Department of Health and Human Services
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半岛bd体育手机客户端 性质
| Quality Level【质量水平】 |
100
|
| biological source【生物来源】 |
mouse
|
| conjugate【偶联物】 |
unconjugated
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| antibody form【抗体形式】 |
purified immunoglobulin
|
| antibody product type |
primary antibodies
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| clone【克隆】 |
2E4, monoclonal
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| form【形式】 |
buffered aqueous solution
|
| species reactivity |
human
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| technique(s) |
indirect ELISA: suitable
western blot: 1-5 μg/mL |
| isotype【同位素/亚型】 |
IgG1κ
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| GenBank?accession no. |
NM_015039
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| UniProt accession no.【UniProt登记号】 |
Q9BZQ4
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| shipped in【运输】 |
dry ice
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| storage temp.【储存温度】 |
?20℃
|
| Gene Information |
human ... NMNAT2(23057)
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半岛bd体育手机客户端 说明
| Disclaimer【免责声明】 |
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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安全信息
| Storage Class Code【储存分类代码】 |
12 - Non Combustible Liquids
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| Personal Protective Equipment【个人防护装备】 |
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
|
