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Monoclonal Anti-LNX2 antibody produced in mouse
| 半岛bd体育手机客户端 编号： | 3147823 |
| 规格： | clone 4F7, purified immunoglobulin, buffered aqueous solution |
| 包装规格： | 100 μG |
| 半岛bd体育手机客户端 类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
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别名
Monoclonal Anti-LNX2 antibody produced in mouse
Anti-PDZRN1
Anti-ligand of numb-protein X 2
Anti-FLJ23932
Anti-MGC46315
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | Ligand of numb-protein X 2 (LNX2) is an E3 ubiquitin ligase and the gene encoding it is localized on chromosome 13q12.2. |
| Immunogen【免疫原】 | LNX2 (NP_699202, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence MGTTSDEMVSVEQTSSSSLNPLCFECGQQHWTRENHLYNYQNEVDDDLVCHICLQPLLQPLDTPCGHTFCYKCLRNFLQEKDFCPLDRKRLHFKLCKKSS |
| Biochem/physiol Actions【生化/生理作用】 | Ligand of numb-protein X 2 (LNX2) modulates NOTCH signaling and WNT/β-catenin pathway. It associates with junction adhesion molecule 4 (JAM 4) and has a role in epithelial-mesenchymal transition. LNX2 has been shown to be upregulated in ovarian cancer. |
| Physical form【外形】 | Solution in phosphate buffered saline, pH 7.4 |
| Legal Information【法律信息】 | GenBank is a registered trademark of United States Department of Health and Human Services |
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性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | 4F7, monoclonal |
| form【形式】 | buffered aqueous solution |
| species reactivity | human |
| technique(s) | indirect ELISA: suitable western blot: 1-5 μg/mL |
| isotype【同位素/亚型】 | IgG2aκ |
| GenBank® accession no. | NM_153371 |
| UniProt accession no.【UniProt登记号】 | Q8N448 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... LNX2(222484) |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | nwg |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |
