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Monoclonal Anti-LIN7A antibody produced in mouse
| 半岛bd体育手机客户端 编号： | 3147785 |
| 规格： | clone GT377, affinity isolated antibody |
| 包装规格： | 100 μL |
| 半岛bd体育手机客户端 类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
半岛bd体育手机客户端 别名
Monoclonal Anti-LIN7A antibody produced in mouse
MALS-1
LIN7
TIP-33
LIN-7A
基本信息
| NACRES |
NA.41
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| Immunogen【免疫原】 |
Recombinant protein encompassing a sequence within the center region of human LIN7A.
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| Application【应用】 |
Suggested starting dilutions are as follows: ICC/IF: 1:100-1:1000, WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
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| Biochem/physiol Actions【生化/生理作用】 |
Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. Required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells.
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| Features and Benefits【特点和优势】 |
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
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| Other Notes【其他说明】 |
Purification: Affinity purified by Protein G
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| Physical form【外形】 |
Phosphate-buffered saline, no preservative added.
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半岛bd体育手机客户端 性质
| Quality Level【质量水平】 |
100
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| biological source【生物来源】 |
mouse
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| conjugate【偶联物】 |
unconjugated
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| antibody form【抗体形式】 |
affinity isolated antibody
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| antibody product type |
primary antibodies
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| clone【克隆】 |
GT377, monoclonal
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| form【形式】 |
buffered aqueous solution
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| mol wt【分子量】 |
26kDa
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| species reactivity |
human
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| concentration【浓度】 |
1mg/mL
|
| technique(s) |
indirect immunofluorescence: suitable
western blot: 500-3000 |
| isotype【同位素/亚型】 |
IgG2b
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| UniProt accession no.【UniProt登记号】 |
O14910
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| shipped in【运输】 |
wet ice
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| storage temp.【储存温度】 |
?20℃
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| Gene Information |
human ... LIN7A(8825)
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半岛bd体育手机客户端 说明
| Disclaimer【免责声明】 |
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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安全信息
| Storage Class Code【储存分类代码】 |
12 - Non Combustible Liquids
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| WGK |
WGK 1
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