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Monoclonal Anti-DNMT2 antibody produced in mouse
| 半岛bd体育手机客户端 编号： | 3144243 |
| 规格： | clone 1E12, purified immunoglobulin, buffered aqueous solution |
| 包装规格： | 100 μG |
| 半岛bd体育手机客户端 类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
半岛bd体育手机客户端 别名
Monoclonal Anti-DNMT2 antibody produced in mouse
Anti-DNA (cytosine-5-)-methyltransferase 2
Anti-PuMet
Anti-M.HsaIIP
基本信息
| MDL number |
MFCD03845290
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| NACRES |
NA.41
|
| General description【一般描述】 |
This gene encodes a protein responsible for the methylation of aspartic acid transfer RNA. While similar in sequence and structure to DNA cytosine methyltransferases, this gene is distinct and highly conserved in its function among taxa. Alternative splicing results in multiple transcript variants encoding different isoforms. (provided by RefSeq)
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| Immunogen【免疫原】 |
DNMT2 (AAH47733, 1 a.a. ~ 391 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence MEPLRVLELYSGVGGMHHALRESCIPAQVVAAIDVNTVANEVYKYNFHHTQLLAKTIEGITLEEFDRLSFDMILMSPPCQPFTRIGRQGDMTDSRTNSFLYILDILPRLQKLPKYILLENVKGFEVSSTRDLLIQTIENCGFQYQEFLLSPTSLGIPNSRLRYFLIAKLQSEPLPFQAPGQVLMEFPKIESVHPQKYAMDVEEKIQEKNVEPNISFDGSIQCSGKDAILFKLETAEEIHRKNQQDSDLSVKMLKDFLEDDTDVNQYLLPPKSLLRYALLLDIVQPTCRRSVCFTKGYGSYIEGTGSVLQTAEDVQVENIYKSLTNLSQEEQITKLLILKLRYFTPKEIANLLGFPPEFGFPEKITVKQRYRLLGNSLNVHVVAKLIKILYE |
| Biochem/physiol Actions【生化/生理作用】 |
DNA methyltransferase 2 (DNMT2) might be involved in
de novomethylation of newly integrated retroviral DNA in mammalian DNA. DNMT2 functions as a tRNA methyltransferase in lower eukaryotes. DNMT2 plays an essential role in zebrafish development by enhancing cytoplasmic RNA methylation. DNMT2 promotes DNA methylation in Drosophila.
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| Physical form【外形】 |
Solution in phosphate buffered saline, pH 7.4
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| Legal Information【法律信息】 |
GenBank is a registered trademark of United States Department of Health and Human Services
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半岛bd体育手机客户端 性质
| Quality Level【质量水平】 |
100
|
| biological source【生物来源】 |
mouse
|
| conjugate【偶联物】 |
unconjugated
|
| antibody form【抗体形式】 |
purified immunoglobulin
|
| antibody product type |
primary antibodies
|
| clone【克隆】 |
1E12, monoclonal
|
| form【形式】 |
buffered aqueous solution
|
| species reactivity |
human
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| technique(s) |
indirect ELISA: suitable
indirect immunofluorescence: suitable western blot: 1-5 μg/mL |
| isotype【同位素/亚型】 |
IgG1λ
|
| GenBank?accession no. |
BC047733
|
| UniProt accession no.【UniProt登记号】 |
O14717
|
| shipped in【运输】 |
dry ice
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| storage temp.【储存温度】 |
?20℃
|
| Gene Information |
human ... TRDMT1(1787)
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半岛bd体育手机客户端 说明
| Disclaimer【免责声明】 |
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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安全信息
| Storage Class Code【储存分类代码】 |
12 - Non Combustible Liquids
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| Personal Protective Equipment【个人防护装备】 |
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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