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Monoclonal Anti-DEPC-1 antibody produced in mouse
| 半岛bd体育手机客户端 编号： | 3144054 |
| 规格： | clone 2A5-4F5, purified immunoglobulin, buffered aqueous solution |
| 包装规格： | 100 μG |
| 半岛bd体育手机客户端 类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
半岛bd体育手机客户端 别名
Monoclonal Anti-DEPC-1 antibody produced in mouse
Anti-prostate cancer antigen-1
基本信息
| NACRES |
NA.41
|
| General description【一般描述】 |
The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 (MIM 610602) and ALKBH3 are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine (Duncan et al., 2002 [PubMed 12486230]).[supplied by OMIM
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| Immunogen【免疫原】 |
DEPC-1 (AAH15155, 1 a.a. ~ 139 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence MEPNPHWHPVLRTLKNRIEENTGHTFNSLLCNLYRNEKDSVDWHSDDEPSLGRCPIIASLSFGATRTFEMRKKPPPEENGDYTYVERVKIPLDHGTLLIMEGATQADWQHRVPKEYHSREPRVNLTFRTVYPDPRGAPW |
| Biochem/physiol Actions【生化/生理作用】 |
DEPC-1 is a DNA/RNA demethylase which has a high affinity for single-stranded DNA and RNA. It has been shown to demethylate
N
1-methyladenosine in mRNA and tRNA
in vitro. DEPC-1 has a role in the development of prostate cancer and has been linked to urothelial carcinomas.
|
| Physical form【外形】 |
Solution in phosphate buffered saline, pH 7.4
|
| Legal Information【法律信息】 |
GenBank is a registered trademark of United States Department of Health and Human Services
|
半岛bd体育手机客户端 性质
| Quality Level【质量水平】 |
100
|
| biological source【生物来源】 |
mouse
|
| conjugate【偶联物】 |
unconjugated
|
| antibody form【抗体形式】 |
purified immunoglobulin
|
| antibody product type |
primary antibodies
|
| clone【克隆】 |
2A5-4F5, monoclonal
|
| form【形式】 |
buffered aqueous solution
|
| species reactivity |
human
|
| technique(s) |
indirect ELISA: suitable
western blot: 1-5 μg/mL |
| isotype【同位素/亚型】 |
IgG1κ
|
| GenBank?accession no. |
BC015155
|
| UniProt accession no.【UniProt登记号】 |
Q96Q83
|
| shipped in【运输】 |
dry ice
|
| storage temp.【储存温度】 |
?20℃
|
| Gene Information |
human ... ALKBH3(221120)
|
安全信息
| Storage Class Code【储存分类代码】 |
12 - Non Combustible Liquids
|
| WGK |
nwg
|
| Personal Protective Equipment【个人防护装备】 |
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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