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Monoclonal Anti-ACTN4 antibody produced in mouse
| 半岛bd体育手机客户端 编号： | 3140503 |
| 规格： | clone 4D10, purified immunoglobulin, buffered aqueous solution |
| 包装规格： | 100 μG |
| 半岛bd体育手机客户端 类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
半岛bd体育手机客户端 别名
Monoclonal Anti-ACTN4 antibody produced in mouse
Anti-FSGS
Anti-FSGS1
Anti-actinin, alpha 4
基本信息
| NACRES |
NA.41
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| General description【一般描述】 |
Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Mutations in this gene have been associated with focal and segmental glomerulosclerosis. (provided by RefSeq)
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| Immunogen【免疫原】 |
ACTN4 (NP_004915, 592 a.a. ~ 701 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence KEAQRIAESNHIKLSGSNPYTTVTPQIINSKWEKVQQLVPKRDHALLEEQSKQQSNEHLRRQFASQANVVGPWIQTKMEEIGRISIEMNGTLEDQLSHLKQYERSIVDYK |
| Features and Benefits【特点和优势】 |
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
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| Physical form【外形】 |
Solution in phosphate buffered saline, pH 7.4
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| Legal Information【法律信息】 |
GenBank is a registered trademark of United States Department of Health and Human Services
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半岛bd体育手机客户端 性质
| Quality Level【质量水平】 |
100
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| biological source【生物来源】 |
mouse
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| conjugate【偶联物】 |
unconjugated
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| antibody form【抗体形式】 |
purified immunoglobulin
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| antibody product type |
primary antibodies
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| clone【克隆】 |
4D10, monoclonal
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| form【形式】 |
buffered aqueous solution
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| species reactivity |
mouse, human, rat
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| technique(s) |
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
indirect ELISA: suitable indirect immunofluorescence: suitable western blot: 1-5 μg/mL |
| isotype【同位素/亚型】 |
IgG2aκ
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| GenBank?accession no. |
NM_004924
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| UniProt accession no.【UniProt登记号】 |
O43707
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| shipped in【运输】 |
dry ice
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| storage temp.【储存温度】 |
?20℃
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| Gene Information |
human ... ACTN4(81)
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半岛bd体育手机客户端 说明
| Disclaimer【免责声明】 |
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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安全信息
| Storage Class Code【储存分类代码】 |
12 - Non Combustible Liquids
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| Personal Protective Equipment【个人防护装备】 |
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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