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3
1α-Hydroxyvitamin D3
| 半岛bd体育手机客户端 编号： | 3117231 |
| 规格： | ≥97.0% (HPLC) |
| CAS NO： | 41294-56-8 |
| 包装规格： | 1 MG |
| 半岛bd体育手机客户端 类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
半岛bd体育手机客户端 价格
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| 半岛bd体育手机客户端 编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3117231 | 1 MG | 4600 |
半岛bd体育手机客户端 别名
41294-56-8
1α-Hydroxyvitamin D3
Alfacalcidol
1α-Hydroxycholecalciferol
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 |
C
27H
44O
2
|
| Molecular weight |
400.64
|
| EC number【EC 号】 |
255-297-1
|
| MDL number |
MFCD00868328
|
| PubChem Substance ID【PubChem化学物质编号】 |
57647693
|
| NACRES |
NA.79
|
| General description【一般描述】 |
1α-Hydroxyvitamin D
3, also known as alfacalcidol, is a synthetic vitamin D
3analogue, hydroxylated in position one. It is metabolized to 1,25-dihydroxycholecalciferol by 25-hydroxylases.
|
| Biochem/physiol Actions【生化/生理作用】 |
1α-Hydroxyvitamin D
3facilitates calcium absorption and deposition. It also has an ability to inhibit bone resorption and stimulate bone formation. Alfacalcidol is used for treating various bone diseases such as rickets/osteomalacia, renal osteodystrophy and osteoporosis. It acts as a chemopreventive agent and reduces the risk colitis and carcinogenesis.
Synthetic vitamin D 3analog that is metabolized to 1,25-dihydroxycholecalciferol. Inhibits bone resorption and stimulates bone formation. Supresses parathyroid hormone secretion by bovine parathyroid cells. |
半岛bd体育手机客户端 性质
| Quality Level【质量水平】 |
100
|
| biological source【生物来源】 |
synthetic
|
| Assay【测定】 |
≥97.0% (HPLC)
|
| form【形式】 |
powder or crystals
|
| color【颜色】 |
white to off-white
|
| storage temp.【储存温度】 |
?20℃
|
| SMILES string |
CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C3\C[C@@H](O)C[C@H](O)C3=C
|
| InChI |
1S/C27H44O2/c1-18(2)8-6-9-19(3)24-13-14-25-21(10-7-15-27(24,25)5)11-12-22-16-23(28)17-26(29)20(22)4/h11-12,18-19,23-26,28-29H,4,6-10,13-17H2,1-3,5H3/b21-11+,22-12-/t19-,23-,24-,25+,26+,27-/m1/s1
|
| InChI key |
OFHCOWSQAMBJIW-AVJTYSNKSA-N
|
| Gene Information |
human ... VDR(7421)
|
| packaging【包装】 |
Bottomless glass bottle. Contents are inside inserted fused cone.
|
安全信息
| Pictograms【象形图】 |
GHS06
|
| Signal word【警示用语：】 |
Danger
|
| Hazard Statements |
H300
|
| Precautionary Statements |
P301 + P330 + P331 + P310
|
| Hazard Classifications【危险分类】 |
Acute Tox. 1 Oral
|
| Storage Class Code【储存分类代码】 |
6.1B - Non-combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
|
| WGK |
WGK 3
|
| Personal Protective Equipment【个人防护装备】 |
Eyeshields, Faceshields, Gloves, type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
|
