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KC7F2
| 半岛bd体育手机客户端 编号： | 3102482 |
| 规格： | ≥98% (HPLC) |
| CAS NO： | 927822-86-4 |
| 包装规格： | 1 MG，5 MG |
| 半岛bd体育手机客户端 类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
半岛bd体育手机客户端 价格
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| 半岛bd体育手机客户端 编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3102482 | 1 MG | 645 | |||
| 3102482 | 5 MG | 995 |
半岛bd体育手机客户端 别名
927822-86-4
KC7F2
N,N′-(Dithiodi-2,1-ethanediyl)bis[2,5-dichloro-benzenesulfonamide
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 |
C
16H
16Cl
4N
2O
4S
4
|
| Molecular weight |
570.38
|
| MDL number |
MFCD22683809
|
| PubChem Substance ID【PubChem化学物质编号】 |
329825637
|
| NACRES |
NA.77
|
| Biochem/physiol Actions【生化/生理作用】 |
KC7F2 is a cell permeable potent HIF-1 pathway inhibitor. KC7F2 inhibits the activation of HIF-target genes such as carbonic anhydrase IX, matrix metalloproteinase 2 (MMP2), enolase 1, and endothelin 1. KC7F2 suppresses the protein accumulation of HIF-1? in cancer cell lines by inhibition of its protein synthesis at the translation level. KC7F2 is preferentially cytotoxicity to cancer cells, an effect that is increased in hypoxia.
|
| Features and Benefits【特点和优势】 |
This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
|
| Other Notes【其他说明】 |
air sensitive
|
半岛bd体育手机客户端 性质
| Quality Level【质量水平】 |
100
|
| Assay【测定】 |
≥98% (HPLC)
|
| form【形式】 |
powder
|
| color【颜色】 |
white to beige
|
| solubility【溶解性】 |
DMSO: 20 mg/mL, clear
|
| shipped in【运输】 |
wet ice
|
| storage temp.【储存温度】 |
?20℃
|
| SMILES string |
ClC1=CC=C(Cl)C=C1S(NCCSSCCNS(C2=C(Cl)C=CC(Cl)=C2)(=O)=O)(=O)=O
|
| InChI |
1S/C16H16Cl4N2O4S4/c17-11-1-3-13(19)15(9-11)29(23,24)21-5-7-27-28-8-6-22-30(25,26)16-10-12(18)2-4-14(16)20/h1-4,9-10,21-22H,5-8H2
|
| InChI key |
REQLACDIZMLXIC-UHFFFAOYSA-N
|
| packaging【包装】 |
1, 5 mg in glass bottle
|
安全信息
| Storage Class Code【储存分类代码】 |
13 - Non Combustible Solids
|
| WGK |
WGK 3
|
