半岛bd体育手机客户端 说明
一般描述
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards
生化/生理作用
Safinamide is a highly selective and reversible monoamine oxidase type B (MAO-B) inhibitor that increases neostriatal dopamine concentration. In addition, safinamide is voltage-dependent sodium and calcium channel blocker. It appears to bind to the batrachotoxin-sensitive site 2 of the voltage-sensitive sodium channels. Safinamide blocks N and L-type calcium channels and inhibits glutamate and aspartate release from synaptic terminals.
分析说明
These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.
其他说明
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
附注
To see an example of a Certificate of Analysis for this material enter LRAC4350 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.
基本信息
| 经验(实验)分子式 | C17H19FN2O2· xCH4O3S |
| 分子量 | 302.34 (free base basis) |
| MDL编号 | MFCD15145475 |
半岛bd体育手机客户端 性质
| 等级 | certified reference material pharmaceutical secondary standard |
| 形式 | powder |
| CofA | current certificate can be downloaded |
| 包装 | pkg of 50 mg |
| 储存温度 | 2-8℃ |
| SMILES string | CS(O)(=O)=O.C[C@H](NCc1ccc(OCc2cccc(F)c2)cc1)C(N)=O |
| InChI | 1S/C17H19FN2O2.CH4O3S/c1-12(17(19)21)20-10-13-5-7-16(8-6-13)22-11-14-3-2-4-15(18)9-14;1-5(2,3)4/h2-9,12,20H,10-11H2,1H3,(H2,19,21);1H3,(H,2,3,4)/t12-;/m0./s1 |
| InChI key | YKOCHIUQOBQIAC-YDALLXLXSA-N |
| Gene Information | human ... MAOB(4129) |
安全信息
| 象形图 |   |
| 警示用语： | Warning |
| 危险声明 | H302 - H319 - H361d |
| 预防措施声明 | P202 - P264 - P270 - P301 + P312 - P305 + P351 + P338 - P308 + P313 |
| 危险分类 | Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2 |
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
SUPELCO
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