半岛bd体育手机客户端 说明
一般描述
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards
生化/生理作用
Perindopril erbumine is an angiotensin converting enzyme (ACE) inhibitor; antihypertensive; becomes hydrolyzedin vivoto the active diacid metabolite; unlike the other ACE inhibitors, inhibits tumor growth in hepatocellular carcinoma cells due to suppression of VEGF levels; also suppresses angiotensin II productionin vitro. Long-term therapy with this agent has a beneficial effect on the cerebral circulation by improving cerebral perfusion reserve in patients with previous minor stroke.
分析说明
These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.
其他说明
This Certified Reference Material (CRM) is produced and certified in accordance withISO 17034andISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
附注
To see an example of a Certificate of Analysis for this material enter LRAB0641 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.
基本信息
经验(实验)分子式 | C19H32N2O5· C4H11N |
分子量 | 441.60 |
MDL编号 | MFCD02313824 |
NACRES | NA.24 |
半岛bd体育手机客户端 性质
质量水平 | 300 |
等级 | certified reference material pharmaceutical secondary standard |
形式 | solid |
CofA | current certificate can be downloaded |
包装 | pkg of 500 mg |
application(s) | pharmaceutical |
药典可追溯性 | traceable to BP 1073 traceable to PhEur Y0000238 traceable to USP 1510889 |
储存温度 | 2-8℃ |
SMILES string | CC(C)(C)N.CCC[C@H](N[C@@H](C)C(=O)N1[C@H]2CCCC[C@H]2C[C@H]1C(O)=O)C(=O)OCC |
InChI | 1S/C19H32N2O5.C4H11N/c1-4-8-14(19(25)26-5-2)20-12(3)17(22)21-15-10-7-6-9-13(15)11-16(21)18(23)24;1-4(2,3)5/h12-16,20H,4-11H2,1-3H3,(H,23,24);5H2,1-3H3/t12-,13-,14-,15-,16-;/m0./s1 |
InChI key | IYNMDWMQHSMDDE-MHXJNQAMSA-N |
Gene Information | human ... ACE(1636) |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
SUPELCO