半岛bd体育手机客户端 说明

一般描述

Bergamottin, a member of the furanocoumarin family, is primarily found in grapefruit juice. It is reported to be a novel signal transducer and activator of the transcription 3 (STAT3) inhibitor. It is a known drug inhibitor of cytochrome P450 34A and also exhibits diverse anti-tumor and anti-inflammatory activities.

应用

Bergamottin may be used as an analytical standard to test its efficacy in the following:

• Blocker of STAT3 activation pathway in tumor cells; its potential in the therapy of multiple myeloma (MM) and other cancers is investigated.
• Prevention and the treatment of cancer via suppression of the NF-kB signaling pathway and its regulated gene products.

包装

Bottomless glass bottle. Contents are inside inserted fused cone.

基本信息

经验(实验)分子式	C21H22O4
分子量	338.40
Beilstein	1353914
MDL编号	MFCD00017409
PubChem化学物质编号	329747253
NACRES	NA.24

半岛bd体育手机客户端 性质

等级	analytical standard
质量水平	100
测定	≥98.0% (HPLC)
technique(s)	HPLC: suitable gas chromatography (GC): suitable
mp	75-80 ℃
application(s)	food and beverages
格式	neat
储存温度	2-8℃
SMILES string	C\C(C)=C\CC\C(C)=C\COc1c2C=CC(=O)Oc2cc3occc13
InChI	1S/C21H22O4/c1-14(2)5-4-6-15(3)9-11-24-21-16-7-8-20(22)25-19(16)13-18-17(21)10-12-23-18/h5,7-10,12-13H,4,6,11H2,1-3H3/b15-9+
InChI key	DBMJZOMNXBSRED-OQLLNIDSSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)