半岛bd体育手机客户端 说明
一般描述
Famotidine is a histamine H2-receptor antagonist, which promotes the healing of erosive esophagitis, gastric and duodenal ulcers since it inhibits the gastric acid secretion in humans.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
应用
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Famotidine may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using different chromatography techniques.
生化/生理作用
H2histamine receptor antagonist; anti-ulcer agent
分析说明
These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.
其他说明
This Certified Reference Material (CRM) is produced and certified in accordance withISO 17034andISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
附注
To see an example of a Certificate of Analysis for this material enter LRAA7133 in the slot below. This is an example certificate only and may not be the lot that you receive.
基本信息
经验(实验)分子式 | C8H15N7O2S3 |
分子量 | 337.45 |
MDL编号 | MFCD00079297 |
PubChem化学物质编号 | 329823085 |
NACRES | NA.24 |
半岛bd体育手机客户端 性质
质量水平 | 300 |
生物来源 | synthetic |
等级 | certified reference material pharmaceutical secondary standard |
agency | BP EP USP |
蒸汽压 | <0.0000001 kPa ( 25 ℃) |
CofA | current certificate can be downloaded |
包装 | pkg of 1 g |
储存条件 | protect from light (20 mm aluminium crimp seal for unused portion) |
technique(s) | HPLC: suitable gas chromatography (GC): suitable |
颜色 | white to pale yellow-white |
mp | 325.4-327.2 °F (163—164℃) |
溶解性 | DMF: freely soluble acetone: practically insoluble chloroform: practically insoluble ethanol: practically insoluble ether: practically insoluble ethyl acetate: practically insoluble glacial acetic acid: freely soluble methanol: slightly soluble water: very slightly soluble |
application(s) | pharmaceutical (small molecule) |
格式 | neat |
药典可追溯性 | traceable to BP 653 traceable to PhEur F0050000 traceable to USP 1269200 |
运输 | ambient |
储存温度 | 2-8℃ |
SMILES string | N\C(N)=N\c1nc(CSCCC(=N)NS(N)(=O)=O)cs1 |
InChI | 1S/C8H15N7O2S3/c9-6(15-20(12,16)17)1-2-18-3-5-4-19-8(13-5)14-7(10)11/h4H,1-3H2,(H2,9,15)(H2,12,16,17)(H4,10,11,13,14) |
InChI key | XUFQPHANEAPEMJ-UHFFFAOYSA-N |
Gene Information | human ... HRH2(3274) |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 2 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
SUPELCO