半岛bd体育手机客户端 说明
一般描述
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Propofol is approved for induction and maintenance of paediatric anesthesia and sedation in children less than 3 years of age. The mechanism of action involves interaction with gamma-aminobutyric acid A receptor. Rapid effect and fewer side effects like postoperative nausea makes propofol a popular intravenous anesthetic agents.
应用
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Propofol may be used as a pharmaceutical reference standard for the determination of the analyte in emulsion dosage form by sequential injection technique with spectrophotometric and fluorimetric detections.
分析说明
These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.
其他说明
This Certified Reference Material (CRM) is produced and certified in accordance withISO 17034andISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
附注
To see an example of a Certificate of Analysis for this material enter LRAA5999 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.
基本信息
| 线性分子式 | [(CH3)2CH]2C6H3OH |
| 分子量 | 178.27 |
| EC 号 | 218-206-6 |
| MDL编号 | MFCD00008885 |
| PubChem化学物质编号 | 329823540 |
| NACRES | NA.24 |
半岛bd体育手机客户端 性质
| 质量水平 | 300 |
| 等级 | certified reference material pharmaceutical secondary standard |
| 蒸汽压 | 5.6 mmHg ( 100 ℃) |
| CofA | current certificate can be downloaded |
| 包装 | ampule of 1 mL |
| technique(s) | HPLC: suitable gas chromatography (GC): suitable |
| 折射率 | n
|
| bp | 256 ℃/764 mmHg (lit.) |
| mp | 18 ℃ (lit.) |
| 密度 | 0.962 g/mL at 25 ℃ (lit.) |
| application(s) | pharmaceutical (small molecule) |
| 格式 | neat |
| 药典可追溯性 | traceable to BP 1031 traceable to PhEur Y0000016 traceable to USP 1572503 |
| 储存温度 | 2-8℃ |
| SMILES string | CC(C)c1cccc(C(C)C)c1O |
| InChI | 1S/C12H18O/c1-8(2)10-6-5-7-11(9(3)4)12(10)13/h5-9,13H,1-4H3 |
| InChI key | OLBCVFGFOZPWHH-UHFFFAOYSA-N |
| Gene Information | human ... GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA4(2557), GABRA5(2558), GABRA6(2559), GABRB1(2560), GABRB2(2561), GABRB3(2562), GABRD(2563), GABRE(2564), GABRG1(2565), GABRG2(2566), GABRG3(2567), GABRP(2568), GABRQ(55879) |
安全信息
| 象形图 |  |
| 警示用语： | Warning |
| 危险声明 | H302 - H315 - H319 - H335 |
| 预防措施声明 | P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338 |
| 危险分类 | Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
| 靶器官 | Respiratory system |
| 储存分类代码 | 10 - Combustible liquids |
| WGK | WGK 3 |
| 闪点(F) | 235.4 °F - closed cup |
| 闪点(C) | 113 ℃ - closed cup |
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