Technical Notes:
1. This catalyst is used for an efficient synthesis of HCV Protease Inhibitor, BILN 206 1
The nitro- Grela catalyst is a stable olefin metathesis initiator active in various ring-closing, cross, and enyne metathesis reactions. Its efficiency has been proven in numerous total syntheses of natural and biologically active compounds, and in material science (see Ref.1-9) References: 1. Org. L ett., 2008, 10, 1303. 2.Org. Process Res. Dev., 2009, 13, 250. 3.Org. L ett., 2013, 15, 1016. 4.Chem. Eur. J., 2013, 19, 11847. 5.Org. L ett., 2010, 12, 248. 6.Angew. Chem. Int. Ed.. 2008. 47, 6483. 7.Tetrahedron L ett, 2006, 47, 6351 8.J. Am. Chem. Soc., 2004, 126, 9318. 9.Angew. Chem. Int. Ed.. 2002. 41.4038.Strem