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位置: 首页> 品牌> Sigma-Aldrich> Anti-TADA3L antibody produced in rabbit

Anti-TADA3L antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB2102358
规格纯度
affinity isolated antibody
价格
6305.78 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
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半岛bd体育手机客户端 名称:
Anti-TADA3L antibody produced in rabbit
Anti-Ada3
Anti-Flj20221
Anti-Hada3
Anti-Transcriptional adaptor 3 (NGG1 homolog, yeast)-like
Anti-Flj21329
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

免疫原

Synthetic peptide directed towards the middle region of human TADA3L

生化/生理作用

Adaptor proteins are usually required for transcriptional activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter.TADA3L is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. In addition, it associates with the tumor suppressor protein p53 and is required for full activity of p53 and p53-mediated apoptosis. Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. In addition, it associates with the tumor suppressor protein p53 and is required for full activity of p53 and p53-mediated apoptosis. At least four alternatively spliced variants have been found for this gene, but the full-length nature of some variants has not been determined.

序列

Synthetic peptide located within the following region: AAVADKKKGLMGPLTELDTKDVDALLKKSEAQHEQPEDGCPFGALTQRLL

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 49 kDa
species reactivity horse, dog, mouse, rabbit, rat, human, bovine, guinea pig
浓度 0.5 mg - 1 mg/mL
technique(s) western blot: suitable
UniProt登记号 O75528
运输 wet ice
储存温度 ?20℃
Gene Information human ... TADA3L(10474)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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