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位置: 首页> 品牌> Sigma-Aldrich> Anti-SLC45A2 antibody produced in rabbit

Anti-SLC45A2 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
AV43780
规格纯度
affinity isolated antibody
价格
5732.41 *本价格含增值税费
促销
服务
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  • 增值税票
数量
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半岛bd体育手机客户端 名称:
Anti-SLC45A2 antibody produced in rabbit
Anti-solute carrier family 45, member 2
Anti-MATP
Anti-1A1
Anti-AIM1
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Solute carrier family 45, member 2/melanoma antigen AIM1/membrane-associated transporter protein (SLC45A2, 1A1, AIM1, MATP) is a skin pigmentation protein involved in melanin biosynthesis. SLC45A2 is a melanoma-associated protein. Defective MATP is a cause of the hypopigmention condition oculocutaneous albinism type 4 (OCA4).

特异性

Anti-SLC45A2 polyclonal antibody reacts with human, mouse, rat, pig, bovine, and canine solute carrier family 45, member 2 proteins.

免疫原

Synthetic peptide directed towards the C terminal region of human SLC45A2

应用

Anti-SLC45A2 polyclonal antibody is used to tag solute carrier family 45, member 2 for detection and quantitation by Western blotting and in plasma by immunohistochemical (IHC) techniques. It is used as a probe to determine the roles of solute carrier family 45, member 2 in melanin biosynthesis, pigmentation and melanoma development.

生化/生理作用

SLC45A2 is a melanocyte differentiation antigen that is expressed in a high percentage of melanoma cell lines. A similar sequence gene in medaka, ′B,′ encodes a transporter that mediates melanin synthesis. Mutations in this gene are a cause of oculocutaneous albinism type 4.The protein encoded by this gene encodes a melanocyte differentiation antigen that is expressed in a high percentage of melanoma cell lines. A similar sequence gene in medaka, ′B,′ encodes a transporter that mediates melanin synthesis. Mutations in this gene are a cause of oculocutaneous albinism type 4. Alternative splicing results in multiple transcript variants encoding different isoforms.

序列

Synthetic peptide located within the following region: IGWTAFLSNMLFFTDFMGQIVYRGDPYSAHNSTEFLIYERGVEVGCWGFC

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 51 kDa
species reactivity human, rat
浓度 0.5 mg - 1 mg/mL
technique(s) western blot: suitable
NCBI登记号 NP_057264
UniProt登记号 Q6P2P0
运输 wet ice
储存温度 ?20℃
Gene Information human ... SLC45A2(51151)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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