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位置: 首页> 品牌> Sigma-Aldrich> Anti-PRPF19 (AB1) antibody produced in rabbit

Anti-PRPF19 (AB1) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
AV43157
规格纯度
IgG fraction of antiserum
价格
3311.54 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
Anti-PRPF19 (AB1) antibody produced in rabbit
Anti-NMP200
Anti-hPSO4
Anti-PRP19
Anti-PSO4
Anti-UBOX4
Anti-PRP19/PSO4 pre-mRNA processing factor 19 homolog ( S. cerevisiae)
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

免疫原

Synthetic peptide directed towards the N terminal region of human PRPF19

生化/生理作用

PRPF19 plays a role in DNA double-strand break (DSB) repair and pre-mRNA splicing reaction. It binds double-stranded DNA in a sequence-nonspecific manner. PRPF19 acts as a structural component of the nuclear framework. It may also serve as a support for spliceosome binding and activity. It is essential for spliceosome assembly in a oligomerization-dependent manner and might also be important for spliceosome stability. It also may have E3 ubiquitin ligase activity. The PSO4 complex is required in the DNA interstrand cross-links (ICLs) repair process. Overexpression of PRPF19 might extend the cellular life span by increasing the resistance to stress or by improving the DNA repair capacity of the cells.In S. cerevisiae, Pso4 has pleiotropic functions in DNA recombination and in error-prone nonhomologous end-joining DNA repair.[supplied by OMIM].

序列

Synthetic peptide located within the following region: VPEHPCVSPVSNHVYERRLIEKYIAENGTDPINNQPLSEEQLIDIKVAHP

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
偶联物 unconjugated
抗体形式 IgG fraction of antiserum
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 55 kDa
species reactivity guinea pig, mouse, dog, horse, rat, human, rabbit, bovine
浓度 0.5 mg - 1 mg/mL
technique(s) western blot: suitable
NCBI登记号 NP_055317
UniProt登记号 Q9UMS4
运输 wet ice
储存温度 ?20℃
Gene Information human ... PRPF19(27339)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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