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位置: 首页> 品牌> Sigma-Aldrich> Anti-PPP1R13L antibody produced in rabbit

Anti-PPP1R13L antibody produced in rabbit

品牌
Sigma-Aldrich
货号
AV32826
规格纯度
affinity isolated antibody
价格
6305.78 *本价格含增值税费
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半岛bd体育手机客户端 名称:
Anti-PPP1R13L antibody produced in rabbit
Anti-NKIP1
Anti-RAI
Anti-IASPP
Anti-iASPPgene
Anti-Protein phosphatase 1, regulatory (inhibitor) subunit 13 like
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Rabbit polyclonal anti- PPP1R13L antibody reacts with mouse, human, bovine, and canine protein phosphatase 1, regulatory (inhibitor) subunit 13 like/RelA-associated inhibitor/inhibitory member of the ASPP family proteins.
Protein phosphatase 1, regulatory (inhibitor) subunit 13 like/RelA-associated inhibitor/inhibitory member of the ASPP family (PPP1R13L, RAI, IASPP, NKIP1) is an inhibitor of p53-dependent apoptosis that may play an important roles in pathologies such as leukemogenesis, disease progression of acute leukemias (AL) and pituitary tumorigenesis.

免疫原

Synthetic peptide directed towards the middle region of human PPP1R13L

应用

Rabbit polyclonal anti- PPP1R13L antibody is used to tag protein phosphatase 1, regulatory (inhibitor) subunit 13 like/RelA-associated inhibitor/inhibitory member of the ASPP family for detection and quantitation by immunocytochemical and immunohistochemical (IHC) techniques. It is used as a probe to determine the presence and roles of protein phosphatase 1, regulatory (inhibitor) subunit 13 like/RelA-associated inhibitor/inhibitory member of the ASPP family in the regulation of p53-dependent functions such as apoptosis and tumor survival and progression.
Rabbit Anti-PPP1R13L antibody can be used for western blot applications at a concentration of 0.25μg/ml.

生化/生理作用

IASPP is one of the most evolutionarily conserved inhibitors of p53 (TP53), whereas ASPP1 and ASPP2 are activators of p53.IASPP is one of the most evolutionarily conserved inhibitors of p53 (TP53; MIM 191170), whereas ASPP1 (MIM 606455) and ASPP2 (MIM 602143) are activators of p53.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

序列

Synthetic peptide located within the following region: AQSVPELEEVARVLAEIPRPLKRRGSMEQAPAVALPPTHKKQYQQIISRL

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 89 kDa
species reactivity bovine, rat, human, horse, pig, mouse, dog
浓度 0.5 mg - 1 mg/mL
technique(s) immunohistochemistry: suitable
western blot: suitable
NCBI登记号 NP_001135974
UniProt登记号 Q8WUF5
运输 wet ice
储存温度 ?20℃
Gene Information human ... PPP1R13L(10848)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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