Anti-POLR2B (AB2) antibody produced in rabbit

半岛bd体育手机客户端 说明

一般描述

POLR2B is a subunit of the RNA polymerase II that synthesises mRNA in cells. This subunit links DNA, nascent mRNA and the enzyme active site during transcription.
Rabbit Anti-POLR2B antibody recognizes human, mouse, rat, canine, bovine, and chicken POLR2B.

免疫原

Synthetic peptide directed towards the N terminal region of human POLR2B

应用

Rabbit Anti-POLR2B (AB2) antibody can be used for western blot applications at a concentration of 5μg/ml.

生化/生理作用

POLR2B is the second largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit, in combination with at least two other polymerase subunits, forms a structure within the polymerase that maintains contact in the active site of the enzyme between the DNA template and the newly synthesized RNA.

序列

Synthetic peptide located within the following region: TYSAPLYVDITKTVIKEGEEQLQTQHQKTFIGKIPIMLRSTYCLLNGLTD

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES

NA.41

半岛bd体育手机客户端 性质

生物来源	rabbit
质量水平	100
偶联物	unconjugated
抗体形式	IgG fraction of antiserum
antibody product type	primary antibodies
克隆	polyclonal
形式	buffered aqueous solution
分子量	134 kDa
species reactivity	rabbit, horse, dog, mouse, rat, guinea pig, human, bovine
浓度	0.5 mg - 1 mg/mL
technique(s)	western blot: suitable
NCBI登记号	NP_000929
UniProt登记号	P30876
运输	wet ice
储存温度	?20℃
Gene Information	human ... POLR2B(5431)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable