半岛bd体育手机客户端 说明
一般描述
PHLPP2 (PH domain and leucine-rich repeat protein phosphatases 2) is a membrane-bound protein with dual functions as a tumor suppressor and a protein phosphatase. It mediates dephosphorylation of ′Ser-473′ of AKT1, ′Ser-660′ of PRKCB isoform beta-II and ′Ser-657′ of PRKCA as well as AKT3 phosphorylation. Dephosphorylation of AKT1, PRKCA and PRKCB leads to their destabilization and degradation and inhibits cancer cell proliferation.
免疫原
Synthetic peptide derived from human PHLPP2 protein.
特点和优势
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外形
0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
半岛bd体育手机客户端 性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 重组 | expressed in proprietary host |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | SP220, monoclonal |
| species reactivity | human (tested) |
| species reactivity (predicted by homology) | mouse |
| technique(s) | immunoblotting: 1:400 immunohistochemistry: 1:100 |
| 同位素/亚型 | IgG |
| UniProt登记号 | Q6ZVD8 |
| 运输 | wet ice |
| 储存温度 | 2-8℃ |
| Gene Information | human ... PHLPP2(23035) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
