ANTI-NUP88 (C-TERM) antibody produced in rabbit

半岛bd体育手机客户端 说明

一般描述

NUP88 (Nucleoporin 88kDa) is an 88kDa non-FG nucleoporin. It acts as a component of a novel nuclear pore complex (NPC). It consists of a C-terminal coiled-coil domain and an interaction domain. It is localized in the cytoplasmic surface of nuclear pore complexes (NPCs). NUP88 consists of two domains, N-terminal and C-terminal domains and its N-terminal and C-terminal domains have been predicted to form β-propeller and a coiled-coil domain.

应用

ANTI-NUP88 (C-TERM) antibody produced in rabbit is suitable for western blot analysis at a dilution of 1:250-1:500.

生化/生理作用

NUP88 (Nucleoporin 88kDa) participates in trafficking between the nucleus and cytoplasm. Its N-terminal β-propeller domain interacts with the FG (phenylalanine-glycine) repeat domain of nucleoporin CAN/Nup214. Further, it binds directly to CRM-1/exportin-1, the receptor for export of most proteins from the nucleus. Nup88 also possesses the ability to bind to the other FG nucleoporins Nup358 and Nup98. Overexpression of NUP88 has been observed in several types of malignancies such as colorectal cancer (CRC) and breast cancer cells.

外形

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES

NA.41

半岛bd体育手机客户端 性质

生物来源	rabbit
质量水平	100
偶联物	unconjugated
抗体形式	IgG fraction of antiserum
antibody product type	primary antibodies
克隆	polyclonal
形式	buffered aqueous solution
分子量	83542 Da
species reactivity	human
technique(s)	western blot: 1:1000
NCBI登记号	NP_002523.2
UniProt登记号	Q99567
运输	wet ice
储存温度	?20℃

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	nwg
闪点(F)	Not applicable
闪点(C)	Not applicable