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位置: 首页> 品牌> Sigma-Aldrich> Anti-NSMCE2 antibody produced in rabbit

Anti-NSMCE2 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB2103989
规格纯度
affinity isolated antibody
价格
6305.78 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
Anti-NSMCE2 antibody produced in rabbit
Anti-NSE2
Anti-FLJ32440
Anti-MMS21
Anti-C8orf36
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

免疫原

Synthetic peptide directed towards the middle region of human NSMCE2

生化/生理作用

NSMCE2 is the E3 SUMO-protein ligase component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. NSMCE2 acts as a E3 ligase mediating SUMO attachment to various proteins such as SMC6L1 and TRAX, and maybe the cohesin components RAD21 and STAG2. SUMO protein-ligase activity is required for the prevention of DNA damage-induced apoptosis by facilitating DNA repair.

序列

Synthetic peptide located within the following region: KFLALQSKNSDADFQNNEKFVQFKQQLKELKKQCGLQADREADGTEGVDE

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 28 kDa
species reactivity rabbit, human, horse
浓度 0.5 mg - 1 mg/mL
technique(s) western blot: suitable
NCBI登记号 NM_173685
UniProt登记号 Q96MF7
运输 wet ice
储存温度 ?20℃
Gene Information human ... NSMCE2(286053)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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