Anti-NRG1 antibody produced in rabbit

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免疫原

Synthetic peptide directed towards the middle region of human NRG1

应用

Anti-NRG1 antibody produced in rabbit is suitable for western blotting at a concentration of 0.5μg/mL.

生化/生理作用

NRG1 (Neuregulin 1) gene encodes a 44kDa single-pass type I membrane protein that associates with NEU/ERBB2 receptor tyrosine kinase and stimulates its phosphorylation on tyrosine residues. NRG1 is a multifunctional protein that exists in various isoforms that play a pivotal role in the development of the peripheral nervous system and during the process of nerve repair. It also has a role in growth and development of multiple organ systems. Additionally, it facilitates the expression and activation of neurotransmitter receptors like glutamate receptors. The dysregulation of the gene leads to schizophrenia, cancer or bipolar disorder (BPD).

序列

Synthetic peptide located within the following region: SEVQVTVQGDKAVVSFEPSAAPTPKNRIFAFSFLPSTAPSFPSPTRNPEV

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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