Anti-NDRG1 (AB2) antibody produced in rabbit

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一般描述

N-myc downstream regulated 1 (NDRG1) is a cytoplasmic hydrolase that modulates stress, hormonal responses, cell growth, differentiation and LDL receptor trafficking. It mediates antimetastatic effects in cancer cells and is downregulated in prostate cancer cells.
Rabbit Anti-NDRG1 antibody recognizes canine, human, mouse, rat, chicken, and bovine NDRG1.

免疫原

Synthetic peptide directed towards the N terminal region of human NDRG1

应用

Rabbit Anti-NDRG1 antibody is suitable for western blot applications at a concentration of 2.5μg/ml.

生化/生理作用

NDRG1 is a member of the N-myc downregulated protein family which belongs to the alpha/beta hydrolase superfamily. NDRG1 is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. Mutation in its gene has been reported to be causative for hereditary motor and sensory neuropathy-Lom.This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. Mutation in this gene has been reported to be causative for hereditary motor and sensory neuropathy-Lom.

序列

Synthetic peptide located within the following region: MSREMQDVDLAEVKPLVEKGETITGLLQEFDVQEQDIETLHGSVHVTLCG

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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