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Anti-MIER1 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
AV34468
规格纯度
IgG fraction of antiserum
价格
3311.54 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
Anti-MIER1 antibody produced in rabbit
Anti-Mesoderm induction early response 1 homolog ( Xenopus laevis)
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

MIER1 is a transcriptional regulator that may repress transcription by blocking the function of histone acetyltransferase.
Rabbit Anti-MIER1 antibody recognizes zebrafish, rabbit, bovine, chicken, canine, human, mouse, and rat MIER1.

免疫原

Synthetic peptide directed towards the middle region of human MIER1

应用

Rabbit Anti-MIER1 antibody can be used for western blot application at a concentration of 1.25 μg/ml.

生化/生理作用

The association of hMI-ER1 with Sp1 represents a novel mechanism for the negative regulation of Sp1 target promoters. Results demonstrate that alternate use of a facultative intron regulates the subcellular localization of hMI-ER1 proteins and this may have important implications for hMI-ER1 function in the regulation of transcription. Repressor activity is due to interaction and recruitment of a trichostatin A-sensitive histone deacetylase 1 (HDAC1).

序列

Synthetic peptide located within the following region: RRTGDEKGVEAIPEGSHIKDNEQALYELVKCNFDTEEALRRLRF

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
偶联物 unconjugated
抗体形式 IgG fraction of antiserum
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 49 kDa
species reactivity rabbit, dog, guinea pig, mouse, horse, bovine, human, rat
浓度 0.5 mg - 1 mg/mL
technique(s) western blot: suitable
NCBI登记号 NP_001071170
UniProt登记号 Q8NES5
运输 wet ice
储存温度 ?20℃
Gene Information human ... MIER1(57708)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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