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Anti-MICA antibody produced in rabbit

品牌
Sigma-Aldrich
货号
AV44247
规格纯度
IgG fraction of antiserum
价格
3311.54 *本价格含增值税费
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数量
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半岛bd体育手机客户端 名称:
Anti-MICA antibody produced in rabbit
Anti-MGC111087
Anti-MHC class I polypeptide-related sequence A
Anti-PERB11.1
Anti-DAQB-48K1.7
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

免疫原

Synthetic peptide directed towards the middle region of human MICA

应用

Anti-MICA antibody produced in rabbit is suitable for western blotting at a concentration of 2.5μg/ml.

生化/生理作用

MHC Class I polypeptide-related sequences A and B (MICA and MICB) are surface glycoproteins expressed constitutively on the enterocytes. They act as ligands for the natural killer group 2, member D (NKG2D) immunoreceptor activation. MICA binds NKG2D receptor and activates the CD8+T cells. Tissue damage or increased expression of MICA results in auto-antibodies detected in early-onset systemic lupus erythematosus and celiac disease.

序列

Synthetic peptide located within the following region: LRRTVPPMVNVTRSEASEGNITVTCRASGFYPWNITLSWRQDGVSLSHDT

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
偶联物 unconjugated
抗体形式 IgG fraction of antiserum
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 42 kDa
species reactivity human
浓度 0.5 mg - 1 mg/mL
technique(s) western blot: suitable
NCBI登记号 NP_000238
UniProt登记号 Q29983
运输 wet ice
储存温度 ?20℃
Gene Information human ... MICA(4276)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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